Computational Protein Design

Ilan Samish Humana

The aim this volume is to present the methods, challenges, software, and applications of this widespread and yet still evolving and maturing field. Computational Protein Design, the first book with this title, guides readers through computational protein design approaches, software and tailored solutions to specific case-study targets. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Protein Design aims to ensure successful results in the further study of this vital field.

ISBN10 : 1493966359 , ISBN13 : 9781493966356

Page Number : 0

An Evidence Based Approach To Vitamins And Minerals

Jane Higdon Thieme

Organized by nutrient, this evidence-based reference synthesizes all of the most current research on vitamins and minerals in an easy-to-use format. Each chapter addresses the function the nutrient plays in the human body; current definitions of deficiency, including Recommended Dietary Allowance (RDA) or Adequate Intake (AI) recommendations; the use of the nutrient for prevention or treatment of a disease, if known; dietary and other sources of the nutrient, including food and supplement sources (breaking down the different supplement forms); safety precautions for overdosing and drug interactions; and the Linus Pauling Institute's current recommendation for health maintenance. Each chapter has been reviewed by an expert in the area, all of whom are noted in the Editorial Advisory Board. This work is endorsed by the Linus Pauling Institute of Oregon State University. Four appendices add to the clinical usefulness of this work: a quick reference to disease prevention and treatment recommendations made throughout the text, nutrient - nutrient interactions, drug - nutrient interactions, and a glossary.

ISBN10 : 1588901246 , ISBN13 : 9781588901248

Page Number : 290

The Chaos Scenario

Bob Garfield

What happens when the old mass media/mass marketing model collapses and the Brave New World is unprepared to replace it? In this fascinating, terrifying, instructive and often hilarious book, Bob Garfield of NPR and Ad Age, chronicles the disintegration of traditional media and marketing but also travels five continents to discover how business can survive--and thrive--in a digitally connected, Post-Media Age. He calls this the art and science of Listenomics. You should listen, too.

ISBN10 : STANFORD:36105134482525 , ISBN13 :

Page Number : 308

Canadian Immunization Guide

Canada. National Advisory Committee on Immunization

The seventh edition of the Canadian Immunization Guide was developed by the National Advisory Committee on Immunization (NACI), with the support ofthe Immunization and Respiratory Infections Division, Public Health Agency of Canada, to provide updated information and recommendations on the use of vaccines in Canada. The Public Health Agency of Canada conducted a survey in 2004, which confi rmed that the Canadian Immunization Guide is a very useful and reliable resource of information on immunization.

ISBN10 : 0660193922 , ISBN13 : 9780660193922

Page Number : 392

Active Pharmaceutical Ingredients In Synthesis

Anthony J. Burke John Wiley & Sons

Presents the most effective catalytic reactions in use today, with a special focus on process intensification, sustainability, waste reduction, and innovative methods This book demonstrates the importance of efficient catalytic transformations for producing pharmaceutically active molecules. It presents the key catalytic reactions and the most efficient catalytic processes, including their significant advantages over compared previous methods. It also places a strong emphasis on asymmetric catalytic reactions, process intensification (PI), sustainability and waste mitigation, continuous manufacturing processes as enshrined by continuous flow catalysis, and supported catalysis. Active Pharmaceutical Ingredients in Synthesis: Catalytic Processes in Research and Development offers chapters covering: Catalysis and Prerequisites for the Modern Pharmaceutial Industry Landscape; Catalytic Process Design - The Industrial Perspective; Hydrogenation, Hydroformylation and Other Reductions; Oxidation; ; Catalytic Addition Reactions; Catalytic Cross-Coupling Reactions; Catalytic Metathesis Reactions; Catalytic Cycloaddition Reactions: Coming Full-Circle; Catalytic Cyclopropanation Reactions; Catalytic C-H insertion Reactions; Phase Transfer Catalysis; and Biocatalysis. -Provides the reader with an updated clear view of the current state of the challenging field of catalysis for API production -Focuses on the application of catalytic methods for the synthesis of known APIs -Presents every key reaction, including Diels-Alder, CH Insertions, Metal-catalytic coupling-reactions, and many more -Includes recent patent literature for completeness Covering a topic of great interest for synthetic chemists and R&D researchers in the pharmaceutical industry, Active Pharmaceutical Ingredients in Synthesis: Catalytic Processes in Research and Development is a must-read for every synthetic chemist working with APIs.

ISBN10 : 9783527342419 , ISBN13 : 3527342419

Page Number : 450

Workplace Drug Testing

Alain G. Verstraete Pharmaceutical Press

This comprehensive text provides clear explanations of the effects of drugs on human performance and the need for workplace drug testing. It provides essential information on the regulatory and legal frameworks around the world, how to set policies and coverage of all aspects of drug analysis and the associated interpretation of results.Contents include:* epidemiology of drug use in the working population* the evidence base and guidelines for workplace drug testing* legal, regulatory aspects and policies for drugs and alcohol* urine and alternative sample collection process* analytical techniques and specimen adulteration.Case studies of successful programmes are also included to illustrate the principles discussed.Written by internationally acknowledged experts this informative book will be essential reading for anyone interested in workplace drug testing or setting up such a system including clinical and forensic toxicologists, occupational health physicians, nurses, human resources, drug counselling and treatment providers, analytical chemists and lawyers.Alain Verstraete is Professor at the Department of Clinical Chemistry, Microbiology and Immunology, Ghent University, Ghent, Belgium and Department Head of the Toxicology Laboratory of the Laboratory of Clinical Biology, Ghent University Hospital, Ghent, Belgium.

ISBN10 : 9780853696940 , ISBN13 : 0853696942

Page Number : 461