Biopharmaceutical Manufacturing Volume

Sarfaraz K. Niazi IOP Publishing Limited

This two-volume set provides a comprehensive guide to the essential aspects of commercial biopharmaceutical manufacturing. Covering the planning, layout and operation of successful commercial manufacturing, the aim of the books is to enable innovations, new drug development, and make affordable biological drugs available to patients worldwide. This volume covers the regulatory processes involved in producing a GMP (Good Manufacturing Practice) biopharmaceutical product for commercial distribution, including areas of current GMP, registration, and legal and ethical considerations. Emerging trends in the technology and regulatory compliance are also discussed, with advice on establishing efficient manufacturing facilities. Intended for practitioners in the commercial biopharmaceutical manufacturing industry, the text is an ideal resource for practitioners looking to develop their ability to manufacture biopharmaceutical products at a large scale. Key Features: Covers the essential aspects of commercial biopharmaceutical manufacturing for industry practitioners, including the planning, layout and operation Provides sufficient information for industry practitioners to establish and operate GMP (Good Manufacturing Practice) compliant manufacturing operations Includes case studies and step-by-step procedures for manufacturing specific biopharmaceutical products Focused exclusively on products intended for human use Includes coverage of regulatory requirements, intellectual property challenges, training of manufacturing teams and issues around cost optimisation

ISBN10 : 0750331739 , ISBN13 : 9780750331739

Page Number : 0

Structural Health Monitoring From Sensing To Processing

Magd Abdel Wahab BoD – Books on Demand

Structural health monitoring (SHM) has attracted more attention during the last few decades in many engineering fields with the main aim of avoiding structural disastrous events. This aim is achieved by using advanced sensing techniques and further data processing. SHM has experienced booming advancements during recent years due to the developments in sensing techniques. The reliable operation of current, sophisticated, man-made structures drives the development of incipient reliable damage diagnosis and assessment. This book aims to illustrate the background and applications of SHM from both sensing and processing approaches. Its main objective is to summarize the advantages and disadvantages of SHM methodologies and their applications, which may provide a new perspective in understanding SHM for readers from diverse engineering fields.

ISBN10 : 9781789237870 , ISBN13 : 1789237874

Page Number : 192

Diagnostic And Therapeutic Applications Of Exosomes In Cancer

Mansoor M. Amiji Academic Press

Diagnostic and Therapeutic Applications of Exosomes in Cancer evaluates the potential of exosome content manipulation in the development of novel therapeutics. In recent years, exosomes, the small vesicles produced by all cell types, have been identified as contributors to cancer growth and metastasis. However, due to their unique biophysical properties, they are also being tested for use in therapeutic design and delivery, as well as in diagnostics. This book presents a comprehensive analysis on exosomes, with a main emphasis on their biogenesis and signaling, use as biomarkers, and as tools for imaging, drug delivery and the treatment of cancer. Covers emerging pharmaceutical and diagnostic applications, including exosomes being tested as carriers of anticancer drugs, ongoing clinical trials, and exosomes as imaging agents for cancer diagnosis and treatment Brings together a team of highly regarded international authors who provide a full-rounded analysis Presents comprehensive coverage of the unique biophysical properties of exosomes Explores current and future possibilities

ISBN10 : 9780128128046 , ISBN13 : 0128128046

Page Number : 400

Multibody Dynamics

Carlo L. Bottasso Springer Science & Business Media

Multibody Dynamics is an area of Computational Mechanics which blends together various disciplines such as structural dynamics, multi-physics - chanics, computational mathematics, control theory and computer science, in order to deliver methods and tools for the virtual prototyping of complex mechanical systems. Multibody dynamics plays today a central role in the modeling, analysis, simulation and optimization of mechanical systems in a variety of ?elds and for a wide range of industrial applications. The ECCOMAS Thematic Conference on Multibody Dynamics was ini- ated in Lisbon in 2003, and then continued in Madrid in 2005 with the goal of providing researchers in Multibody Dynamics with appropriate venues for exchanging ideas and results. The third edition of the Conference was held at the Politecnico di Milano, Milano, Italy, from June 25 to June 28, 2007. The Conference saw the participation of over 250 researchers from 32 di?- ent countries, presenting 209 technical papers, and proved to be an excellent forum for discussion and technical exchange on the most recent advances in this rapidly growing ?eld.

ISBN10 : 9781402088292 , ISBN13 : 1402088299

Page Number : 252

Green Electrospinning

Nesrin Horzum Walter de Gruyter GmbH & Co KG

The last two decades have seen electrospinning of nanofibers performed mainly from solutions of toxic organic solvents. The increase in demand for scaling up electrospinning in recent years therefore requires an environmentally friendly process free of organic solvents. This book addresses techniques for clean and safe electrospinning in the fabrication of green nanofibers and their potential applications.

ISBN10 : 9783110588637 , ISBN13 : 3110588633

Page Number : 405

Regenerative Medicine For The Treatment Of Urinary Incontinence

Klaudia Stangel-Wójcikiewicz

This monograph addresses an innovative autologous muscle-derived stem cell therapy for urinary incontinence in women. It provides a detailed overview of studies and research projects on the use of stem cells for the treatment of urinary incontinence. It provides updated information about this condition for the era of regenerative medicine, making it a valuable resource for both students and physicians.

ISBN10 : 8323341494 , ISBN13 : 9788323341499

Page Number : 82